Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor hemoglobin loss

Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor hemoglobin loss

Abstract Background Bone marrow (BM) transplantation is a life-saving therapy for hematological diseases, and the BM harbors also highly useful (progenitor) cell types for novel cell therapies manufacture. Yet, the BM collection technique is not standardized. Methods Benchmarking our collection effi...

Full description

Bibliographic Details
Main Authors: Jeremy Epah, Gabriele Spohn, Kathrin Preiß, Markus M. Müller, Johanna Dörr, Rainer Bauer, Shabnam Daqiq-Mirdad, Joachim Schwäble, Stefanie N. Bernas, Alexander H. Schmidt, Erhard Seifried, Richard Schäfer
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Medicine
Subjects:
Bone marrow
Collection
Transplantation
Stem cells
Anemia
MSCs
Online Access:https://doi.org/10.1186/s12916-023-03059-3

Internet

https://doi.org/10.1186/s12916-023-03059-3

Similar Items