Prothrombin complex concentrate versus placebo, no intervention, or other interventions in critically bleeding patients associated with oral anticoagulant administration: a protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

Prothrombin complex concentrate versus placebo, no intervention, or other interventions in critically bleeding patients associated with oral anticoagulant administration: a protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

Abstract Background Acute critical bleeding is one of the most feared complications during treatment with oral anticoagulating agents. As more patients undergo treatment with anticoagulating agents, critically bleeding episodes in patients with vitamin K antagonists, thrombin inhibitor, or factor Xa...

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Bibliographic Details
Main Authors: Christian Ovesen, Jan Purrucker, Christian Gluud, Janus Christian Jakobsen, Hanne Christensen, Thorsten Steiner
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Systematic Reviews
Subjects:
Critical bleeding
Oral anticoagulation
Prothrombin complex concentrate
Intracranial haemorrhage
Online Access:http://link.springer.com/article/10.1186/s13643-018-0838-y

Internet

http://link.springer.com/article/10.1186/s13643-018-0838-y

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