NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia

NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia

Conventional chemotherapy for acute myeloid leukemia regimens generally encompass an intensive induction phase, in order to achieve a morphological remission in terms of bone marrow blasts (<5%). The majority of cases are classified as Primary Induction Response (PIR); unfortunately, 15% of child...

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Bibliographic Details
Main Authors: Vincenza Barresi, Virginia Di Bella, Nellina Andriano, Anna Provvidenza Privitera, Paola Bonaccorso, Manuela La Rosa, Valeria Iachelli, Giorgia Spampinato, Giulio Pulvirenti, Chiara Scuderi, Daniele F. Condorelli, Luca Lo Nigro
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
acute myeloid leukemia
chemotherapy resistance
omics technologies
transcriptome profile
dysregulated genes
NUP98-rearrangements
Online Access:https://www.mdpi.com/1422-0067/22/9/4575

Internet

https://www.mdpi.com/1422-0067/22/9/4575

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