Roles of Endomembrane Alkali Cation/Proton Exchangers in Synaptic Function and Neurodevelopmental Disorders

Roles of Endomembrane Alkali Cation/Proton Exchangers in Synaptic Function and Neurodevelopmental Disorders

Endomembrane alkali cation (Na+, K+)/proton (H+) exchangers (eNHEs) are increasingly associated with neurological disorders. These eNHEs play integral roles in regulating the luminal pH, processing, and trafficking of cargo along the secretory (Golgi and post-Golgi vesicles) and endocytic (early, re...

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Bibliographic Details
Main Authors: Andy Y. L. Gao, Etienne Lourdin-De Filippis, John Orlowski, R. Anne McKinney
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Physiology
Subjects:
endomembranes
alkali cation/proton exchangers
pH regulation
synaptic function
neurodevelopmental disorders
autism
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.892196/full

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https://www.frontiersin.org/articles/10.3389/fphys.2022.892196/full

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