The Safety and Efficacy of Nanosecond Pulsed Electric Field in Patients With Hepatocellular Carcinoma: A Prospective Phase 1 Clinical Study Protocol

The Safety and Efficacy of Nanosecond Pulsed Electric Field in Patients With Hepatocellular Carcinoma: A Prospective Phase 1 Clinical Study Protocol

BackgroundHepatocellular carcinoma (HCC) is a highly aggressive malignancy. Irreversible electroporation (IRE) is an ablative modality that uses high-voltage electrical pulses to permeabilize the cell membrane leading to cell necrosis. Unlike traditional thermal ablation, IRE is hardly affected by t...

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Bibliographic Details
Main Authors: Min Xu, Danxia Xu, Gang Dong, Zhigang Ren, Wu Zhang, Tuerganaili Aji, Qiyu Zhao, Xinhua Chen, Tian’an Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
nanosecond pulsed electric field (nsPEF)
irreversible electroporation (IRE)
hepatocellular carcinoma (HCC)
ablation
protocol
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.869316/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.869316/full

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