Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo assessments

Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo assessments

The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-loaded novasomes aiming to enhance drug corneal penetration and to improve its antifungal activity. Ethanol injection was used to formulate FTN-loaded novasomes adopting a central composite design. The researched...

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Bibliographic Details
Main Authors: Sadek Ahmed, Maha M. Amin, Sarah Mohamed El-Korany, Sinar Sayed
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
Fenticonazole Nitrate
central composite design
gamma sterilization
corneal permeation
susceptibility test
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2103600

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https://www.tandfonline.com/doi/10.1080/10717544.2022.2103600

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