Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3.

Rabies is a neglected zoonotic disease that has no effective treatment after onset of illness. However the disease can be prevented effectively by prompt administration of post exposure prophylaxis which includes administration of passive immunizing antibodies (Rabies Immune Globulin, RIG). Currentl...

Full description

Bibliographic Details
Main Authors: Tsepo Lebiletsa Tsekoa, Therese Lotter-Stark, Sindisiwe Buthelezi, Ereck Chakauya, Stoyan H Stoychev, Claude Sabeta, Wonderful Shumba, Baby Phahladira, Steve Hume, Josh Morton, Charles E Rupprecht, Herta Steinkellner, Michael Pauly, Larry Zeitlin, Kevin Whaley, Rachel Chikwamba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4948892?pdf=render