AMIGO2 contained in cancer cell-derived extracellular vesicles enhances the adhesion of liver endothelial cells to cancer cells

Abstract Adhesion of cancer cells to vascular endothelial cells in target organs is an initial step in cancer metastasis. Our previous studies revealed that amphoterin-induced gene and open reading frame 2 (AMIGO2) promotes the adhesion of tumor cells to liver endothelial cells, followed by the form...

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Bibliographic Details
Main Authors: Runa Izutsu, Mitsuhiko Osaki, Hideyuki Nemoto, Maho Jingu, Ryo Sasaki, Yusuke Yoshioka, Takahiro Ochiya, Futoshi Okada
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04662-1