Genetic determinants of complement activation in the general population

Genetic determinants of complement activation in the general population

Summary: Complement is a fundamental innate immune response component. Its alterations are associated with severe systemic diseases. To illuminate the complement’s genetic underpinnings, we conduct genome-wide association studies of the functional activity of the classical (CP), lectin (LP), and alt...

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Bibliographic Details
Main Authors: Damia Noce, Luisa Foco, Dorothea Orth-Höller, Eva König, Giulia Barbieri, Maik Pietzner, Dariush Ghasemi-Semeskandeh, Stefan Coassin, Christian Fuchsberger, Martin Gögele, Fabiola Del Greco M., Alessandro De Grandi, Monika Summerer, Eleanor Wheeler, Claudia Langenberg, Cornelia Lass-Flörl, Peter Paul Pramstaller, Florian Kronenberg, Reinhard Würzner, Cristian Pattaro
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cell Reports
Subjects:
CP: Genomics
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723016236

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http://www.sciencedirect.com/science/article/pii/S2211124723016236

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