Complement Suppresses the Initial Type 1 Interferon Response to Ocular Herpes Simplex Virus Type 1 Infection in Mice

The complement system (CS) contributes to the initial containment of viral and bacterial pathogens and clearance of dying cells in circulation. We previously reported mice deficient in complement component 3 (C3KO mice) were more sensitive than wild-type (WT) mice to ocular HSV-1 infection, as measu...

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Bibliographic Details
Main Authors: Daniel J. J. Carr, Adrian Filiberti, Grzegorz B. Gmyrek
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/13/1/74