Lower frequency of the low activity adenosine deaminase allelic variant (ADA1*2) in schizophrenic patients Diminuição da frequência da variante alélica de baixa atividade da adenosina desaminase (ADA1*2) em pacientes esquizofrênicos

OBJECTIVE: Adenosine may play a role in the pathophysiology of schizophrenia, since it modulates the release of several neurotransmitters such as glutamate, dopamine, serotonin and acetylcholine, decreases neuronal activity by pos-synaptic hyperpolarization and inhibits dopaminergic activity. Adenos...

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Bibliographic Details
Main Authors: Gustavo Pimentel Dutra, Gustavo L. Ottoni, Diogo R. Lara, Maurício Reis Bogo
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2010-09-01
Series:Brazilian Journal of Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462010000300011