Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner

Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner

Prostaglandin E2 (PGE2) is a key player in a plethora of physiological and pathological events. Nevertheless, little is known about the dynamics of PGE2 secretion from a single cell and its effect on the neighboring cells. Here, by observing confluent Madin–Darby canine kidney (MDCK) epithelial cell...

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Bibliographic Details
Main Authors: Tetsuya Watabe, Shinya Yamahira, Kanako Takakura, Dean Thumkeo, Shuh Narumiya, Michiyuki Matsuda, Kenta Terai
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
prostaglandin E2
imaging
intercellular communication
Online Access:https://elifesciences.org/articles/86727

Internet

https://elifesciences.org/articles/86727

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