Role of crotoxin in coagulation: novel insights into anticoagulant mechanisms and impairment of inflammation-induced coagulation

Role of crotoxin in coagulation: novel insights into anticoagulant mechanisms and impairment of inflammation-induced coagulation

Abstract Background: Snake venom phospholipases A2 (svPLA2) are biologically active toxins, capable of triggering and modulating a wide range of biological functions. Among the svPLA2s, crotoxin (CTX) has been in the spotlight of bioprospecting research due to its role in modulating immune respons...

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Bibliographic Details
Main Authors: Bruna Terada Gimenez, Gabriel Neves Cezarette, Aline de Sousa Bomfim, Wuelton Marcelo Monteiro, Elisa Maria de Sousa Russo, Fabiani Gai Frantz, Suely Vilela Sampaio, Marco Aurelio Sartim
Format: Article
Language:English
Published: SciELO 2020-11-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Crotoxin
Anticoagulant mechanism
Phospholipase A2
Anti-inflammatory activity
Snake venom
Tissue factor
Coagulation factors
Coagulation complex
Coagulation phospholipids
Cytokines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100339&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100339&tlng=en

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