Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

Background: Epilepsy is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches. In the last years the interest on the non-psychoactive compounds pre...

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Bibliographic Details
Main Authors: Elisa Landucci, Costanza Mazzantini, Daniele Lana, Maura Calvani, Giada Magni, Maria Grazia Giovannini, Domenico E. Pellegrini-Giampietro
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Neurobiology of Disease
Subjects:
Cannabinoid
Neurodegeneration
Neuroprotection
Kainate
Organotypic hippocampal slices
CA3 region
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612200287X

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http://www.sciencedirect.com/science/article/pii/S096999612200287X

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