Xenogeneic equine stem cells activate anti-tumor adaptive immunity in a 4T1-based intraductal mouse model for triple-negative breast cancer: proof-of-principle

Xenogeneic equine stem cells activate anti-tumor adaptive immunity in a 4T1-based intraductal mouse model for triple-negative breast cancer: proof-of-principle

Triple-negative breast cancer (TNBC) remains difficult to treat, especially due to ineffective immune responses. Current treatments mainly aim at a cytotoxic effect, whereas (stem) cell therapies are being investigated for their immune stimulatory capacities to initiate the anti-tumor immunity. Here...

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Bibliographic Details
Main Authors: Jonas Steenbrugge, Glenn Pauwelyn, Kristel Demeyere, Nausikaa Devriendt, Hilde de Rooster, Niek N. Sanders, Jan H. Spaas, Evelyne Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
triple-negative breast cancer
intraductal model
immunotherapy
xenogeneic
equine stem cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1252374/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1252374/full

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