Overexpression of RBBP6, alone or combined with mutant TP53, is predictive of poor prognosis in colon cancer.

Retinoblastoma binding protein 6 (RBBP6) plays an important role in chaperone-mediated ubiquitination and interacts with TP53 in carcinogenesis. However, the clinicopathologic significance of RBBP6 expression in colon cancer is unknown; in particular, the prognostic value of RBBP6 combined with TP53...

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Bibliographic Details
Main Authors: Jian Chen, Huamei Tang, Zehua Wu, Chongzhi Zhou, Tao Jiang, Yingming Xue, Guoyu Huang, Dongwang Yan, Zhihai Peng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23799110/pdf/?tool=EBI