A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination

A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination

Systemically vaccinated individuals against COVID-19 and influenza may continue to support viral replication and shedding in the upper airways, contributing to the spread of infections. Thus, a vaccine regimen that enhances mucosal immunity in the respiratory mucosa is needed to prevent a pandemic....

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Bibliographic Details
Main Authors: Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S. Lao, Yukiya Sako, Jasmine Jin, Nikunj M. Shukla, Howard B. Cottam, Michael Chan, Masiel M. Belsuzarri, Dennis A. Carson, Tomoko Hayashi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Vaccines
Subjects:
intranasal pulmonary boosting regimen
influenza virus infection
TLR4 agonist
TLR7 agonist
combination adjuvant
liposomal formulation
Online Access:https://www.mdpi.com/2076-393X/10/10/1694

Internet

https://www.mdpi.com/2076-393X/10/10/1694

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