Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells

Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells

The cytokine erythropoietin (EPO) is a potent inducer of erythrocyte development and one of the most prescribed biopharmaceuticals. The action of EPO on erythroid progenitor cells is well established, but its direct action on hematopoietic stem and progenitor cells (HSPCs) is still debated. Here, us...

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Bibliographic Details
Main Authors: Almut S Eisele, Jason Cosgrove, Aurelie Magniez, Emilie Tubeuf, Sabrina Tenreira Bento, Cecile Conrad, Fanny Cayrac, Tamar Tak, Anne-Marie Lyne, Jos Urbanus, Leïla Perié
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
cellular barcoding
erythropoietin
hematopoietic stem cell
multipotent progenitor
single cell
Online Access:https://elifesciences.org/articles/66922

Internet

https://elifesciences.org/articles/66922

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