CRISPR–Cas9 applications in T cells and adoptive T cell therapies

CRISPR–Cas9 applications in T cells and adoptive T cell therapies

Abstract T cell immunity is central to contemporary cancer and autoimmune therapies, encompassing immune checkpoint blockade and adoptive T cell therapies. Their diverse characteristics can be reprogrammed by different immune challenges dependent on antigen stimulation levels, metabolic conditions,...

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Bibliographic Details
Main Authors: Xiaoying Chen, Shuhan Zhong, Yonghao Zhan, Xuepei Zhang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cellular & Molecular Biology Letters
Subjects:
CRISPR–Cas9
T cells
Adoptive T cell therapy
CAR-T
TCR-T
TIL
Online Access:https://doi.org/10.1186/s11658-024-00561-1

Internet

https://doi.org/10.1186/s11658-024-00561-1

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