Unraveling the Functional Significance of Unstructured Regions in G Protein-Coupled Receptors

Unraveling the Functional Significance of Unstructured Regions in G Protein-Coupled Receptors

Unstructured regions in functional proteins have gained attention in recent years due to advancements in informatics tools and biophysical methods. G protein-coupled receptors (GPCRs), a large family of cell surface receptors, contain unstructured regions in the form of the i3 loop and C-terminus. T...

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Bibliographic Details
Main Authors: Roberto Maggio, Irene Fasciani, Francesco Petragnano, Maria Francesca Coppolino, Marco Scarselli, Mario Rossi
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
G protein-coupled receptor
unstructured protein
third cytoplasmic loop
C-terminus
domain swapping
Online Access:https://www.mdpi.com/2218-273X/13/10/1431

Internet

https://www.mdpi.com/2218-273X/13/10/1431

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