African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation

African Swine Fever Virus pF778R Attenuates Type I Interferon Response by Impeding STAT1 Nuclear Translocation

African swine fever virus (ASFV) is an extensive and intricate double-stranded DNA virus with approximately 100% lethality in domestic swine. There is no effective vaccine to combat this virus, and this has led to substantial economic losses in the swine industry. ASFV encodes various proteins that...

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Bibliographic Details
Main Authors: Qichao Chen, Liang Li, Lixinjie Liu, Zhankui Liu, Shibang Guo, Chen Tan, Huanchun Chen, Xiangru Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Virus Research
Subjects:
African swine fever virus
pF778R
Type I IFN signaling
STAT1 nuclear translocation
Immune evasion
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223001521

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http://www.sciencedirect.com/science/article/pii/S0168170223001521

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