Petrosamine Revisited. Experimental and Computational Investigation of Solvatochromism, Tautomerism and Free Energy Landscapes of a Pyridoacridinium Quaternary Salt

Petrosamine (<b>1</b>)—a colored pyridoacridine alkaloid from the Belizean sponge, <i>Petrosia</i> sp., that is also a potent inhibitor of acetylcholine esterase (AChE)—was investigated by spectroscopic and computational methods. Analysis of the petrosamine-free energy landsc...

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Bibliographic Details
Main Authors: Christopher J. Gartshore, Xiao Wang, Yongxuan Su, Tadeusz F. Molinski
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/21/8/446