Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients.

Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients.

<h4>Background</h4>Tuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to determine whether accurate TB antigen detection in blood or urine has the potential to meet the WHO target product profile...

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Bibliographic Details
Main Authors: Tobias Broger, Michael Tsionksy, Anu Mathew, Todd L Lowary, Abraham Pinter, Tatiana Plisova, Daniel Bartlett, Simone Barbero, Claudia M Denkinger, Emmanuel Moreau, Kiyonori Katsuragi, Masanori Kawasaki, Payam Nahid, George B Sigal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215443

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https://doi.org/10.1371/journal.pone.0215443

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