SIRT1 mediated gastric cancer progression under glucose deprivation through the FoxO1-Rab7-autophagy axis

SIRT1 mediated gastric cancer progression under glucose deprivation through the FoxO1-Rab7-autophagy axis

PurposeSilent mating type information regulator 2 homolog 1 (SIRT1) and autophagy have a two-way action (promoting cell death or survival) on the progression and treatment of gastric cancer (GC) under different conditions or environments. This study aimed to investigate the effects and underlying me...

Full description

Bibliographic Details
Main Authors: Mengke Zhu, Chao Wei, Haijiang Wang, Shangning Han, Lindi Cai, Xiaowen Li, Xinhua Liao, Xiangming Che, Xuqi Li, Lin Fan, Guanglin Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
SIRT1-FoxO1-Rab7
autophagy
target treatment
glucose deprivation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1175151/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1175151/full

Similar Items