ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trial

Abstract Background SARS-CoV-2 infection is associated with a significant risk of hospitalisation, death, and prolonged impact on quality of life. Evaluation of new treatment options and optimising therapeutic management of people hospitalised with SARS-CoV-2 infection remains essential, but rapid c...

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Main Authors: Justin T. Denholm, Balasubramanian Venkatesh, Joshua Davis, Asha C. Bowen, Naomi E. Hammond, Vivekanand Jha, Grace McPhee, Zoe McQuilten, Matthew V. N. O’Sullivan, David Paterson, David Price, Megan Rees, Jason Roberts, Mark Jones, James Totterdell, Thomas Snelling, Nanette Trask, Susan Morpeth, Steven YC Tong, on behalf of the ASCOT ADAPT investigators
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-022-06929-y