HBsAg level defines different clinical phenotypes of HBeAg(−) chronic HBV infection related to HBV polymerase-specific CD8+ cell response quality

HBsAg level defines different clinical phenotypes of HBeAg(−) chronic HBV infection related to HBV polymerase-specific CD8+ cell response quality

BackgroundHBe-antigen(Ag)-negative chronic hepatitis B virus (HBV) infection is characterized by little liver fibrosis progression and vigorous HBV-multispecific CD8+ T-cell response.AimsTo assess whether HBsAg level could discriminate different HBeAg-negative chronic HBV infection subtypes with dis...

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Bibliographic Details
Main Authors: Julia Peña-Asensio, Henar Calvo-Sánchez, Joaquín Miquel-Plaza, Eduardo Sanz-de-Villalobos, Alejandro González-Praetorius, Alberto Delgado-Fernandez, Miguel Torralba, Juan-Ramón Larrubia
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
HBV inactive carrier
functional HBV-specific CD8 + T-cell response
HBV immune control
liver fibrosis progression
HBsAg
HBV eAg(-) infection gray-zone
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1352929/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1352929/full

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