A methodological review with meta-epidemiological analysis of preclinical systematic reviews with meta-analyses

Abstract Systematic reviews and meta-analyses have been proposed as an approach to synthesize the literature and counteract the lack of power of small preclinical studies. We aimed to evaluate (1) the methodology of these reviews, (2) the methodological quality of the studies they included and (3) w...

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Bibliographic Details
Main Authors: Noémie Simon-Tillaux, Anne-Laure Gerard, Deivanes Rajendrabose, Florence Tubach, Agnès Dechartres
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24447-4