G Protein-Coupled Estrogen Receptor: Rapid Effects on Hippocampal-Dependent Spatial Memory and Synaptic Plasticity

G Protein-Coupled Estrogen Receptor: Rapid Effects on Hippocampal-Dependent Spatial Memory and Synaptic Plasticity

In the hippocampus, estrogen regulates gene transcription linked to neuronal growth, neuroprotection, and the maintenance of memory function (1–3). The mechanism is likely to involve genomic regulation through classic estrogen receptor (ER) signaling cascades that influence transcription. Estrogens...

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Bibliographic Details
Main Authors: Ashok Kumar, Thomas C. Foster
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
estrogen
estrogen receptor
GPER
spatial memory
synaptic plasticity
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00385/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00385/full

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