High-Throughput Sequencing of Complementarity Determining Region 3 in the Heavy Chain of B-Cell Receptor in Renal Transplant Recipients: A Preliminary Report

High-Throughput Sequencing of Complementarity Determining Region 3 in the Heavy Chain of B-Cell Receptor in Renal Transplant Recipients: A Preliminary Report

Background: Graft failure resulting from rejection or any other adverse event usually originates from an aberrant and/or exaggerated immune response and is often catastrophic in renal transplantation. So, it is essential to monitor patients’ immune status for detecting a rejection/graft failure earl...

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Bibliographic Details
Main Authors: Tsai-Hung Wu, Hsien-Tzung Liao, Tzu-Hao Li, Hung-Cheng Tsai, Niang-Cheng Lin, Cheng-Yen Chen, Shih-Feng Tsai, Tzu-Hao Huang, Chang-Youh Tsai, Chia-Li Yu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
B cell
immune repertoire (iR)
complementary determining region 3 (CDR3)
renal transplantation
clonal diversity
next-generation sequencing (NGS)
Online Access:https://www.mdpi.com/2077-0383/11/11/2980

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https://www.mdpi.com/2077-0383/11/11/2980

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