SIRT3 Deficiency Sensitizes Angiotensin-II-Induced Renal Fibrosis

SIRT3 Deficiency Sensitizes Angiotensin-II-Induced Renal Fibrosis

Background: Sirtuin 3 (SIRT3) has a crucial role in the cardiovascular diseases. Our previous study revealed that SIRT3 knockout (SIRT3KO) promoted cardiac pericyte–fibroblast transition. In this study, we investigated the involvement of pericyte and iron in angiotensin II (Ang-II)-mediated renal fi...

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Bibliographic Details
Main Authors: Xiaomeng Feng, Han Su, Xiaochen He, Jian-Xiong Chen, Heng Zeng
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
SIRT3 deficiency
hypertension
renal
fibrosis
pericyte
iron overload
Online Access:https://www.mdpi.com/2073-4409/9/11/2510

Internet

https://www.mdpi.com/2073-4409/9/11/2510

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