Duplication and diversification of the hypoxia-inducible IGFBP-1 gene in zebrafish.

Gene duplication is the primary force of new gene evolution. Deciphering whether a pair of duplicated genes has evolved divergent functions is often challenging. The zebrafish is uniquely positioned to provide insight into the process of functional gene evolution due to its amenability to genetic an...

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Bibliographic Details
Main Authors: Hiroyasu Kamei, Ling Lu, Shuang Jiao, Yun Li, Claus Gyrup, Lisbeth S Laursen, Claus Oxvig, Jianfeng Zhou, Cunming Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2518108?pdf=render