ROCK ‘n TOR: An Outlook on Keratinocyte Stem Cell Expansion in Regenerative Medicine via Protein Kinase Inhibition

ROCK ‘n TOR: An Outlook on Keratinocyte Stem Cell Expansion in Regenerative Medicine via Protein Kinase Inhibition

Keratinocyte stem cells play a fundamental role in homeostasis and repair of stratified epithelial tissues. Transplantation of cultured keratinocytes autografts provides a landmark example of successful cellular therapies by restoring durable integrity in stratified epithelia lost to devastating tis...

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Bibliographic Details
Main Authors: Giorgia Centonze, Sara Centonze, Luca Ponzone, Enzo Calautti
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
keratinocyte stem cell
regenerative medicine
cell therapy
mammalian target of rapamycin (mTOR)
Rho-associated protein kinase (ROCK)
rapamycin
Online Access:https://www.mdpi.com/2073-4409/11/7/1130

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https://www.mdpi.com/2073-4409/11/7/1130

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