Efficient Gene Expression in Human Stem Cell Derived-Cortical Organoids Using Adeno Associated Virus

Efficient Gene Expression in Human Stem Cell Derived-Cortical Organoids Using Adeno Associated Virus

Cortical organoids are 3D structures derived either from human embryonic stem cells or human induced pluripotent stem cells with their use exploding in recent years due to their ability to better recapitulate the human brain in vivo in respect to organization; differentiation; and polarity. Adeno-as...

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Bibliographic Details
Main Authors: Ann-Na Cho, Fiona Bright, Nicolle Morey, Carol Au, Lars M. Ittner, Yazi D. Ke
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
cortical organoids
Adeno-associated viruses (AAVs)
TDP-43
gene delivery
neurodegenerative disease
Online Access:https://www.mdpi.com/2073-4409/11/20/3194

Internet

https://www.mdpi.com/2073-4409/11/20/3194

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