MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1

MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1

Abstract Background Discoidin domain receptor-1 (DDR1) tyrosine kinase is highly expressed in a variety of human cancers and involved in various steps of tumorigenesis. However, the precise mechanisms underlying the abnormal expression of DDR1 in oral squamous cell carcinoma (OSCC) has not been well...

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Bibliographic Details
Main Authors: Sung-Tau Chou, Hsuan-Yu Peng, Kuan-Chi Mo, Yuan-Ming Hsu, Guan-Hsun Wu, Jenn-Ren Hsiao, Su-Fang Lin, Horng-Dar Wang, Shine-Gwo Shiah
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-486-3p
DDR1
ANK1
DNA methylation
Oral cancer
OSCC
Online Access:http://link.springer.com/article/10.1186/s13046-019-1283-z

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http://link.springer.com/article/10.1186/s13046-019-1283-z

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