Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment.

BACKGROUND: MicroRNAs (miRNAs) are short non-coding RNAs predicted to regulate one third of protein coding genes via mRNA targeting. In conjunction with key transcription factors, such as the repressor REST (RE1 silencing transcription factor), miRNAs play crucial roles in neurogenesis, which requir...

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Bibliographic Details
Main Authors: Brandon Smith, Julie Treadwell, Dongling Zhang, Dao Ly, Iain McKinnell, P Roy Walker, Marianna Sikorska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2886071?pdf=render