Stabilization of the Quadruplex-Forming G-Rich Sequences in the Rhinovirus Genome Inhibits Uncoating—Role of Na<sup>+</sup> and K<sup>+</sup>

Rhinoviruses (RVs) are the major cause of common cold, a respiratory disease that generally takes a mild course. However, occasionally, RV infection can lead to serious complications in patients debilitated by other ailments, e.g., asthma. Colds are a huge socioeconomic burden as neither vaccines no...

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Bibliographic Details
Main Authors: Antonio Real-Hohn, Martin Groznica, Georg Kontaxis, Rong Zhu, Otávio Augusto Chaves, Leonardo Vazquez, Peter Hinterdorfer, Heinrich Kowalski, Dieter Blaas
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/4/1003