HLA-DR Expression Level in CD8+ T Cells Correlates With the Severity of Children With Acute Infectious Mononucleosis

HLA-DR Expression Level in CD8+ T Cells Correlates With the Severity of Children With Acute Infectious Mononucleosis

BackgroundThis study aimed to assess the host immune signatures associated with EBV infection and its clinical value in indicating the severity of children with acute infectious mononucleosis (IM).MethodsTwenty-eight pediatric patients with IM aged 3–8 years were enrolled. The immune phenotypes and...

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Bibliographic Details
Main Authors: Yun Wang, Ying Luo, Guoxing Tang, Renren Ouyang, Minxia Zhang, Yuhuan Jiang, Ting Wang, Xiwen Zhang, Botao Yin, Jin Huang, Wei Wei, Min Huang, Feng Wang, Shiji Wu, Hongyan Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
EBV
infectious mononucleosis
CD8+ T cells
CD4+ T cells
HLA-DR+ CD8+ T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.753290/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.753290/full

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