Induced hepatic stem cells are suitable for human hepatocyte production

Induced hepatic stem cells are suitable for human hepatocyte production

Summary: Human hepatocytes were transfected with Sendai virus vectors (SeV) expressing OCT3/4, SOX2, KLF4, and C-MYC to produce hepatocyte-derived induced pluripotent stem cells (iPSCs). The messenger RNA (mRNA) expression of undifferentiated markers (passage 19-21) and hepatocyte-specific markers (...

Full description

Bibliographic Details
Main Authors: Yoshiki Nakashima, Chika Miyagi-Shiohira, Issei Saitoh, Masami Watanabe, Masayuki Matsushita, Masayoshi Tsukahara, Hirofumi Noguchi
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Human
biological sciences
cell biology
stem cells research
developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222013244

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222013244

Similar Items