Age-related differences in white matter microstructure measured by advanced diffusion MRI in healthy older adults at risk for Alzheimer’s disease

Age-related differences in white matter microstructure measured by advanced diffusion MRI in healthy older adults at risk for Alzheimer’s disease

Neurite orientation dispersion and density imaging (NODDI) is an advanced diffusion imaging technique, which can detect more distinct microstructural features compared to conventional Diffusion Tensor Imaging (DTI). NODDI allows the signal to be divided into multiple water compartments and derive me...

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Bibliographic Details
Main Authors: Alice Motovylyak, Nicholas M. Vogt, Nagesh Adluru, Yue Ma, Rui Wang, Jennifer M. Oh, Steven R. Kecskemeti, Andrew L. Alexander, Douglas C. Dean, Catherine L. Gallagher, Mark A. Sager, Bruce P. Hermann, Howard A. Rowley, Sterling C. Johnson, Sanjay Asthana, Barbara B. Bendlin, Ozioma C. Okonkwo
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Aging Brain
Subjects:
Aging, Alzheimer’s disease (AD)
Diffusion tensor imaging (DTI)
Magnetic resonance imaging (MRI)
Neurite orientation dispersion and density imaging (NODDI)
White matter
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958922000020

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http://www.sciencedirect.com/science/article/pii/S2589958922000020

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