YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription

YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription

Abstract Yes-associated protein (YAP) activation is crucial for tumor formation and development, and its stability is regulated by ubiquitination. ISGylation is a type of ubiquitination like post-translational modification, whereas whether YAP is ISGylated and how ISGylation influences YAP ubiquitin...

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Bibliographic Details
Main Authors: Xiangfei Xue, Xiaoting Tian, Congcong Zhang, Yayou Miao, Yikun Wang, Yingxiu Peng, Shiyu Qiu, Hong Wang, Jiangtao Cui, Leiqun Cao, Fenyong Sun, Yongxia Qiao, Xiao Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00842-8

Internet

https://doi.org/10.1038/s41420-022-00842-8

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