Lactylation stabilizes DCBLD1 activating the pentose phosphate pathway to promote cervical cancer progression

Lactylation stabilizes DCBLD1 activating the pentose phosphate pathway to promote cervical cancer progression

Abstract Background Discoidin, CUB, and LCCL domain-containing type I (DCBLD1) is identified as an oncogene involved in multiple regulation of tumor progression, but specific mechanisms remain unclear in cervical cancer. Lactate-mediated lactylation modulates protein function. Whether DCBLD1 can be...

Full description

Bibliographic Details
Main Authors: Qingfei Meng, Huihui Sun, Yanghe Zhang, Xiangzhe Yang, Shiming Hao, Bin Liu, Honglan Zhou, Zhi-Xiang Xu, Yishu Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Lactylation
Pentose phosphate pathway
Autophagy
Cervical cancer
G6PD
DCBLD1
Online Access:https://doi.org/10.1186/s13046-024-02943-x

Internet

https://doi.org/10.1186/s13046-024-02943-x

Similar Items