iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency

Abstract Background Patients with immunodeficiency virus-1 (HIV-1) infection are challenging to be cured completely due to the existence of HIV-1 latency reservoirs. However, the knowledge of the mechanisms and biomarkers associated with HIV-1 latency is limited. Therefore, identifying proteins rela...

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Bibliographic Details
Main Authors: Lin Yin, Qimin Wang, Siyuan Liu, Jun Chen, Yujiao Zhang, Lingqing Lu, Hongzhou Lu, Zhigang Song, Lijun Zhang
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Proteome Science
Subjects:
Online Access:https://doi.org/10.1186/s12953-024-00230-3