Individual and Combined Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predict Shorter Survival of Soft Tissue Sarcoma Patients.

Individual and Combined Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predict Shorter Survival of Soft Tissue Sarcoma Patients.

DNA damage response (DDR) molecules are protective against genotoxic stresses. DDR molecules are also involved in the survival of cancer cells in patients undergoing anti-cancer therapies. Therefore, DDR molecules are potential markers of cancer progression in addition to being potential therapeutic...

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Bibliographic Details
Main Authors: Kyoung Min Kim, Young Jae Moon, See-Hyoung Park, Hye Jeong Park, Sung Il Wang, Ho Sung Park, Ho Lee, Keun Sang Kwon, Woo Sung Moon, Dong Geun Lee, Jung Ryul Kim, Kyu Yun Jang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5028069?pdf=render

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http://europepmc.org/articles/PMC5028069?pdf=render

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