Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses

Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses

Background & Aims: HBV exhibits wide genetic diversity with at least 9 genotypes (GTs), which differ in terms of prevalence, geographic distribution, natural history, disease progression, and treatment outcome. However, differences in HBV replicative capacity, gene expression, and infective...

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Bibliographic Details
Main Authors: Yongzhen Liu, Debby Park, Thomas R. Cafiero, Yaron Bram, Vasuretha Chandar, Anna Tseng, Hans P. Gertje, Nicholas A. Crossland, Lishan Su, Robert E. Schwartz, Alexander Ploss
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:JHEP Reports
Subjects:
hepatitis B virus
hepatitis B
viral hepatitis
genotypes
reverse genetics
host responses
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555922001070

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http://www.sciencedirect.com/science/article/pii/S2589555922001070

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