Uric Acid Enhances Neurogenesis in a Parkinsonian Model by Remodeling Mitochondria

Uric Acid Enhances Neurogenesis in a Parkinsonian Model by Remodeling Mitochondria

BackgroundAdult neurogenesis is the process of generating new neurons to enter neural circuits and differentiate into functional neurons. However, it is significantly reduced in Parkinson’s disease (PD). Uric acid (UA), a natural antioxidant, has neuroprotective properties in patients with PD. This...

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Bibliographic Details
Main Authors: Ji Eun Lee, Yu Jin Shin, Yi Seul Kim, Ha Na Kim, Dong Yeol Kim, Seok Jong Chung, Han Soo Yoo, Jin Young Shin, Phil Hyu Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
uric acid
neurogenesis
Parkinson’s disease
mitochondrial dynamics
neural precursor cell
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.851711/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.851711/full

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