Mechanosensitive ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis

Mechanosensitive ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis

Introduction: Pulmonary fibrosis is a major cause of the poor prognosis of acute respiratory distress syndrome (ARDS). While mechanical ventilation (MV) is an indispensable life-saving intervention for ARDS, it may cause the remodeling process in lung epithelial cells to become disorganized and exac...

Full description

Bibliographic Details
Main Authors: Xiang-Zhi Fang, Min Li, Ya-Xin Wang, Pei Zhang, Miao-Miao Sun, Jia-Xin Xu, Yi-Yi Yang, Ya-Jun He, Yuan Yu, Rui-Ting Li, Ting Zhou, Le-Hao Reng, De-Yi Sun, Hua-Qing Shu, Shi-Ying Yuan, Ji-Qian Xu, You Shang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Advanced Research
Subjects:
Mechanical ventilation
Piezo1
Pulmonary fibrosis
Acute respiratory distress syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222002855

Internet

http://www.sciencedirect.com/science/article/pii/S2090123222002855

Similar Items