Novel Insights in the Potential of Halogenated Polyketide–Peptide Molecules as Lead Compounds in Cancer Drug Discovery

Novel Insights in the Potential of Halogenated Polyketide–Peptide Molecules as Lead Compounds in Cancer Drug Discovery

In this interdisciplinary study, we selected two compounds, namely, smenamide A, a peptide–polyketide, and smenolactone D, a polyketide, as models because they are representative of two different classes of molecules isolated from the marine sponge <i>Smenospongia aurea</i>. The organic...

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Bibliographic Details
Main Authors: Valentina Pellicioni, Germana Esposito, Giulia Greco, Ivan Cruz-Chamorro, Fabio Ferrini, Piero Sestili, Roberta Teta, Carmela Fimognari, Valeria Costantino
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Smenospongia aurea</i>
natural products
polyketide
molecular networking
LC-MS
PCD pathways
Online Access:https://www.mdpi.com/1422-0067/24/7/6208

Internet

https://www.mdpi.com/1422-0067/24/7/6208

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