Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography

Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography

Introduction: The misuse of stimulant drugs such as methamphetamine is a global public health issue. One important neurochemical mechanism of methamphetamine use disorder may be altered dopaminergic neurotransmission. For instance, previous studies using positron emission tomography (PET) have consi...

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Bibliographic Details
Main Authors: Kyoji Okita, Toshihiko Matsumoto, Daisuke Funada, Maki Murakami, Koichi Kato, Yoko Shigemoto, Noriko Sato, Hiroshi Matsuda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
methamphetamine
addiction
dopamine D2 receptors
adenosine 2A receptor
neuroinflammation
positron emission tomography
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.820447/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.820447/full

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