Core-dependent post-translational modifications guide the biosynthesis of a new class of hypermodified peptides

Abstract The ribosomally synthesized and post-translationally modified peptide (RiPPs) class of natural products has undergone significant expansion due to the rapid growth in genome sequencing data. Using a bioinformatics approach, we identify the dehydrazoles, a novel class of hypermodified RiPPs...

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Bibliographic Details
Main Authors: Zeng-Fei Pei, Lingyang Zhu, Satish K. Nair
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43604-5