Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-κB Inhibitory Potential

The Ascomycota Dichotomomyces cejpii was isolated from the marine sponge Callyspongia cf. C. flammea. A new gliotoxin derivative, 6-acetylmonodethiogliotoxin (1) was obtained from fungal extracts. Compounds 2 and 3, methylthio-gliotoxin derivatives were formerly only known as semi-synthetic compound...

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Bibliographic Details
Main Authors: Henrik Harms, Barbora Orlikova, Seungwon Ji, Damun Nesaei-Mosaferan, Gabriele M. König, Marc Diederich
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/13/8/4949